1
A 3-year-old child presents with failure to thrive, polyuria, and rickets. Laboratory investigations show metabolic acidosis, hypophosphatemia, glycosuria with normal blood glucose, and generalized aminoaciduria. Which nephron segment is primarily affected in this disorder?
A
Proximal convoluted tubule
B
Thick ascending limb of loop of Henle
C
Distal convoluted tubule