4
A 12-year-old boy presents with severe hypertension, hypokalemia, and metabolic alkalosis. Plasma renin and aldosterone levels are suppressed. Which mechanism best explains this condition?
A
Defect in Na-K-2Cl transporter
B
Overactivation of epithelial sodium channels
C
Proximal tubular bicarbonate wasting
D
Defective Na-Cl cotransporter